A postdoctoral position is available in the laboratory of Dr. Nancy Speck in the Department of Cell and Developmental Biology at the Perelman School of Medicine at the University of Pennsylvania. The candidate will lead multidisciplinary projects aimed at understanding hematopoietic stem cell formation in the embryo, or the mechanisms by which mutations in the transcription factor Runx1 contribute to leukemia.

The Speck laboratory uses genetically engineered mouse models to study hematopoietic stem cell formation in the embryo. Particular areas of interest include the role of Runx1 in embryonic blood cell formation, and the contribution of inflammatory signaling to this process. A second area of interest is how inherited mutations in the RUNX1 gene predispose individuals to developing myelodysplastic syndrome and leukemia, and the role of secondary mutations in disease progression.

We seek highly qualified individuals who are motivated, flexible, collaborative, detail-oriented, have the ability to multitask, and are committed to research excellence. The successful candidate should have a PhD and/or MD degree with a strong background in hematology, molecular biology, cell biology, and/or genomics. Research experience in flow cytometry, microscopy, animal models, and embryology would be advantageous.

Please forward a cover letter, CV, and the names/addresses of 3 references to:

Nancy A. Speck, Ph.D.
Professor and Chair, Department of Cell and Developmental Biology
Perelman School of Medicine
University of Pennsylvania
421 Curie Boulevard
Philadelphia, PA 19104-6160
Subject: Interest in Postdoctoral Position

For other positions in the Speck lab:

Graduate Student: 1st year students from CAMB and other graduate programs should email Dr. Speck directly to discuss potential rotation opportunities and projects.

Research Technician: If positions are available, they will be advertised through the Penn HR website.