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Welcome to: Speck Lab

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Selected Publications

Bellissimo DC, Chen CH, Zhu Q, Bagga S, Lee CT, He B, Wertheim GB, Jordan M, Tan K, Worthen GS, Gilliland DG, Speck NA: Runx1 negatively regulates inflammatory cytokine production by neutrophils in response to Toll-like receptor signaling. Blood Adv. 4(6): 1145-1158 (2020).

Gao P, Chen C, Howell ED, Li Y, Tober J, Uzun Y, He B, Gao L, Zhu Q, Siekmann AF, Speck NA, Tan K: Transcriptional regulatory network controlling the ontogeny of hematopoietic stem cells. Genes Dev. 342(13-14): 950-964 (2020).

Zhu Q, Gao P, Tober J, Bennett L, Chen C, Uzun Y, Li Y, Howell ED, Mumau M, Yu W, He B, Speck NA, Tan K.: Developmental trajectory of prehematopoietic stem cell formation from endothelium. Blood. 136: 845-856 (2020).

Tober J, Maijenburg MMW, Li Y, Gao L, Hadland BK, Gao P, Minoura K, Bernstein ID, Tan K, Speck NA.  Maturation of hematopoietic stem cells from prehematopoietic stem cells is accompanied by up-regulation of PD-L1J Exp Med. 2018 Feb 5;215(2):645-659.