Tober J, Maijenburg MMW, Li Y, Gao L, Hadland BK, Gao P, Minoura K, Bernstein ID, Tan K, Speck NA.  Maturation of hematopoietic stem cells from prehematopoietic stem cells is accompanied by up-regulation of PD-L1J Exp Med. 2018 Feb 5;215(2):645-659.

Yzaguirre AD, Howell ED, Li Y, Liu Z, Speck NA.  Runx1 is sufficient for blood cell formation from non-hemogenic endothelial cells in vivo only during early embryogenesis. Development. 2018 Jan 29;145(2).

Bellissimo DC, Speck NA.  RUNX1 Mutations in Inherited and Sporadic Leukemia. Front Cell Dev Biol. 2017 Dec 20;5:111.

Kulkeaw K, Inoue T, Iino T, Tani K, Akashi K, Speck NA, Nakanishi Y, Sugiyama D.  Twist1 regulates embryonic hematopoietic differentiation through binding to Myb and Gata2 promoter regionsBlood Adv. 2017 Aug 31;1(20):1672-1681.

Oo ZM, Illendula A, Grembecka J, Schmidt C, Zhou Y, Esain V, Kwan W, Frost I, North TE, Rajewski RA, Speck NA, Bushweller JH.  A tool compound targeting the core binding factor Runt domain to disrupt binding to CBFβ in leukemic cellsLeuk Lymphoma. 2017 Dec 18:1-13.

Zhen T, Kwon EM, Zhao L, Hsu J, Hyde RK, Lu Y, Alemu L, Speck NA, Liu PP.  Chd7 deficiency delays leukemogenesis in mice induced by Cbfb-MYH11Blood. 2017 Nov 30;130(22):2431-2442.

 Li Y, Gao L, Hadland B, Tan K, Speck NA.  CD27 marks murine embryonic hematopoietic stem cells and type II prehematopoietic stem cellsBlood. 2017 Jul 20;130(3):372-376.

Kim E, Cheng Y, Bolton-Gillespie E, Cai X, Ma C, Tarangelo A, Le L, Jambhekar M, Raman P, Hayer KE, Wertheim G, Speck NA, Tong W, Viatour P.  Rb family proteins enforce the homeostasis of quiescent hematopoietic stem cells by repressing Socs3 expressionJ Exp Med. 2017 Jul 3;214(7):1901-1912.

Lis R, Karrasch CC, Poulos MG, Kunar B, Redmond D, Duran JGB, Badwe CR, Schachterle W, Ginsberg M, Xiang J, Tabrizi AR, Shido K, Rosenwaks Z, Elemento O, Speck NA, Butler JM, Scandura JM, Rafii S.  Conversion of adult endothelium to immunocompetent haematopoietic stem cellsNature. 2017 May 25;545(7655):439-445.

Yzaguirre AD, de Bruijn MF, Speck NA.  The Role of Runx1 in Embryonic Blood Cell FormationAdv Exp Med Biol. 2017;962:47-64.

Speck NA.  Stress Can Be a Good Thing for Blood Formation.  Cell Stem Cell. 2016 Sep 1;19(3):279-80.

Yzaguirre AD, Speck NA. Insights into blood cell formation from hemogenic endothelium in lesser-known anatomic sites. Dev Dyn. 2016 Jul 8.

Yzaguirre AD, Speck NA. Extravascular endothelial and hematopoietic islands form through multiple pathways in midgestation mouse embryos. Dev Biol. 2016 Jul 1;415(1):111-21.

Yzaguirre AD, Padmanabhan A, de Groh ED, Engleka KA, Li J, Speck NA, Epstein JA. Loss of neurofibromin Ras-GAP activity enhances the formation of cardiac blood islands in murine embryos. Elife. 2015 Oct 13;4:e07780.

Cai X, Gao L, Teng L, Ge J. Oo ZM, Kumar AR, Gilliland DG, Mason PH, Tan K, Speck NA: Runx1 deficiency decreases ribosome biogenesis and confers stress resistance to hematopoietic stem and progenitor cells. Cell Stem Cell 17(2): 165-177, August 2015.

Tamplin OJ, Durand EM, Carr LA, Childs SJ, Hagedorn EJ, Li P, Yzaguirre AD, Speck NA, Zon LI. Hematopoietic stem cell arrival triggers dynamic remodeling of the perivascular niche. Cell. 2015 Jan 15;160(1-2):241-52

Li Y, Esain V, Teng L, Xu J, Kwan W, Frost I, Yzaguirre AD, Cai X, Cortes M, Maijenburg MW, Tober J, Dzierzak E, Orkin SH, Tan K, North TE, Speck NA: Inflammatory signaling regulates embryonic hematopoietic stem and progenitor cell production. Genes & Development 28: 2597-612, Nov 2014.

Tober J, Yzaguirre AD, Piwarzyk E, Speck NA: Distinct temporal requirements for Runx1 in hematopoietic progenitors and stem cells. Development 140(18): 3765-76, Sep 2013.

Chen MJ, Li Y, De Obaldia ME, Yang Q, Yzaguirre AD, Yamada-Inagawa T, Vink CS, Bhandoola A. Dzierzak E. Speck NA: Erythroid/myeloid progenitors and hematopoietic stem cells originate from distinct populations of endothelial cells. Cell Stem Cell 9(6): 541-52, Dec 2011.

Chen M, Yokomizo T, Zeigler B, Speck NA: Runx1 is required for the endothelial to hematopoietic stem cell transition but not thereafter. Nature 457: 887-892 Feb 2009. Notes: Comments by Yoshomito and Yoder, Nature 457, 801-802; Nature Reports Stem Cells (January 19, 2009); Nature Reports Stem Cells (March 12, 2009); Jaffredo and Dieterlen-Lievre, Cell Stem Cell 4, 189-190.